THC
Tetrahydrocannabinol (THC) is a cannabinoid found in cannabis. It is the principal psychoactive constituent of Cannabis and one of at least 113 total cannabinoids identified on the plant. Although the chemical formula for THC (C21H30O2) describes multiple isomers, the term THC usually refers to the delta-9-THC isomer with chemical name (−)-trans-Δ9-tetrahydrocannabinol. It is a colorless oil.
THC, also known pharmaceutically as dronabinol, is used medically to relieve chemotherapy-induced nausea and HIV/AIDS-related anorexia. Nabiximols, a botanical drug which contains THC, is used medically to treat symptoms of multiple sclerosis, including spasticity and neuropathic pain. THC acts as a partial agonist at CB1 and CB2 cannabinoid receptors.
THC can be administered orally, inhaled, or transdermally, with bioavailability and onset varying by route, and is extensively metabolized in the liver to active and inactive metabolites before being excreted in feces and urine. Side effects include red eyes, dry mouth, drowsiness, memory impairment, anxiety, and, with chronic use, cannabinoid hyperemesis syndrome. While human overdose is rare, THC can interact with other drugs and has a complex pharmacokinetic profile.
THC is classified variably under international and US law, with medical use approved in multiple countries. Research supports its effectiveness for spasticity and central pain in multiple sclerosis, though evidence for other neurological disorders is limited, and long-term high-dose exposure may carry uncertain toxicity risks.
Cassette
- 2022-07-15T00:00:00.000000Z
Vibing
- 2021-11-26T00:00:00.000000Z
Tranceycore
- 2021-11-25T00:00:00.000000Z
Tetrising
- 2021-11-24T00:00:00.000000Z
Stomp That
- 2021-11-23T00:00:00.000000Z
My Sound
- 2021-11-22T00:00:00.000000Z
Callin Me
- 2021-11-21T00:00:00.000000Z
One
- 2019-12-16T00:00:00.000000Z
Cocaine
- 2019-09-16T00:00:00.000000Z
Lrad Aca
- 2019-02-25T00:00:00.000000Z
Crazy / Get Up
- 2019-01-14T00:00:00.000000Z
How to Flex
- 2018-12-28T00:00:00.000000Z
Roll It Up
- 2016-06-27T00:00:00.000000Z
Bye
- 2016-02-29T00:00:00.000000Z
Gemini
- 2015-07-27T00:00:00.000000Z
Way Of Life
- 2014-02-12T00:00:00.000000Z
Similar Artists